Dish: Banana-Rum Cream Cake

Banana-Rum Cream Cake

ACTIVE INGREDIENTS:

Butter cookie crumb crust:
1 1/2 mugs carefully ground butter cookies
6 tablespoon saltless butter, thawed

Banana dental filling:
7 ripe bananas, split
3/4 mug entire milk
8 ounces white delicious chocolate, coarsely cut
2 tablespoon dark rum
1 tsp unflavored powdered jelly
3 mugs whipping cream

PREP WORK:

Make the cookie crumb crust:
Placement a shelf in the facility of the stove and also preheat to 350 levels( F). Butter all-time low of a 9-inch springform frying pan.
In a tiny dish, incorporate the ground butter cookies and also thawed butter. Press uniformly right into all-time low of the ready frying pan. Cook for 8 to 10 mins or up until gently browned; alloted to cool down.

Make the banana dental filling:
Cut 5 of the bananas right into 1-inch items and also integrate with the milk in a tool pan. Give an outrage medium-high warmth. Decrease the warm to reduced and also simmer for 5 mins.
In a mixer fitted with a steel blade, mix the banana mix till smooth. Put right into a tool dish and also mix the white delicious chocolate right into the combination till totally thawed; reserved to cool down.
Location the dark rum in a little microwave-safe dish. Spray the jelly over and also allow represent 5 mins to soften.
Mix 1/2 mug of the banana handbag right into the jelly. Fold up the banana jelly blend right into the rest of the banana puree as well as established apart.
Mix 1/4 of the whipped lotion right into the banana filling up to lighten it as well as after that layer in the staying whipped lotion in 3 enhancements. Cut the staying bananas right into 1/4-inch items. Area the banana pieces equally over the base of the crust.
Run a countered spatula around the external side of the pie to loosen up. Eliminate springform ring as well as garnish pie with whipped lotion as well as fresh banana pieces.

Cut 5 of the bananas right into 1-inch items as well as incorporate with the milk in a tool pan. Mix 1/2 mug of the banana handbag right into the jelly. Fold up the banana jelly blend right into the rest of the banana puree as well as established apart.
Mix 1/4 of the whipped lotion right into the banana filling up to lighten it as well as after that layer in the staying whipped lotion in 3 enhancements. Location the banana pieces uniformly over the base of the crust.

Posted 13 Sep 2023 18:03 by | Uncategorized | No comments

Intricate link between siderophore secretion and drug efflux in Mycobacterium tuberculosis | Antimicrobial Agents and Chemotherapy

Seung KJ, Keshavjee S, Rich ML. 2015. Multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. Cold Spring Harb Perspect Med 5:a017863.

Berhanu RH, Schnippel K, Kularatne R, Firnhaber C, Jacobson KR, Horsburgh CR, Lippincott CK. 2018. Can patients afford the cost of treatment for multidrug-resistant tuberculosis in ethiopia Int J Tuberc Lung Dis 22:358–362.

Niederweis M, Danilchanka O, Huff J, Hoffmann C, Engelhardt H. 2010. Mycobacterial outer membranes: in search of proteins. Trends Microbiol 18:109–116.

Jarlier V, Nikaido H. 1994. Mycobacterial cell wall: structure and role in natural resistance to antibiotics. FEMS Microbiol Lett 123:11–18.

Cohen KA, Bishai WR, Pym AS. 2014. Molecular basis of drug resistance in Mycobacterium tuberculosis. Microbiol Spectr 2.

Islam MM, Hameed HMA, Mugweru J, Chhotaray C, Wang C, Tan Y, Liu J, Li X, Tan S, Ojima I, Yew WW, Nuermberger E, Lamichhane G, Zhang T. 2017. Drug resistance mechanisms and novel drug targets for tuberculosis therapy. J Genet Genomics 44:21–37.

Remm S, Earp JC, Dick T, Dartois V, Seeger MA. 2022. Critical discussion on drug efflux in Mycobacterium tuberculosis. FEMS Microbiol Rev 46:fuab050.

Milano A, Pasca MR, Provvedi R, Lucarelli AP, Manina G, Ribeiro AL, Manganelli R, Riccardi G. 2009. Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system. Tuberculosis (Edinb) 89:84–90.

Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A. 2014. Acquired resistance of Mycobacterium tuberculosis to bedaquiline. PLoS One 9:e102135.

Hartkoorn RC, Uplekar S, Cole ST. 2014. Cross-resistance between clofazimine and bedaquiline through upregulation of MmpL5 in Mycobacterium tuberculosis. Antimicrob Agents Chemother 58:2979–2981.

Lange C, Chesov D, Heyckendorf J. 2019. Clofazimine for the treatment of multidrug-resistant tuberculosis. Clin Microbiol Infect 25:128–130.

Stadler JAM, Maartens G, Meintjes G, Wasserman S. 2023. Clofazimine for the treatment of tuberculosis. Front Pharmacol 14:1100488.

Yao G, Zhu M, Nie Q, Chen N, Tu S, Zhou Y, Xiao F, Liu Y, Li X, Chen H. 2023. Improved outcomes following addition of bedaquiline and clofazimine to a treatment regimen for multidrug-resistant tuberculosis. J Int Med Res 51:3000605221148416.

Pang Y, Zong Z, Huo F, Jing W, Ma Y, Dong L, Li Y, Zhao L, Fu Y, Huang H. 2017. In vitro drug susceptibility of bedaquiline, delamanid, linezolid, clofazimine, moxifloxacin, and gatifloxacin against extensively drug-resistant tuberculosis in Beijing, China. Antimicrob Agents Chemother 61:e00900-17.

Guo Q, Bi J, Lin Q, Ye T, Wang Z, Wang Z, Liu L, Zhang G. 2022. Whole genome sequencing identifies novel mutations associated with bedaquiline resistance in Mycobacterium tuberculosis. Front Cell Infect Microbiol 12:807095.

Wells RM, Jones CM, Xi Z, Speer A, Danilchanka O, Doornbos KS, Sun P, Wu F, Tian C, Niederweis M. 2013. Discovery of a siderophore export system essential for virulence of Mycobacterium tuberculosis. PLoS Pathog 9:e1003120.

Jones CM, Wells RM, Madduri AVR, Renfrow MB, Ratledge C, Moody DB, Niederweis M. 2014. Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling. Proc Natl Acad Sci U S A 111:1945–1950.

Zhang L, Hendrickson RC, Meikle V, Lefkowitz EJ, Ioerger TR, Niederweis M, Boshoff HI. 2020. Comprehensive analysis of iron utilization by Mycobacterium tuberculosis. PLoS Pathog 16:e1008337.

Zhang L., Kent JE, Whitaker M, Young DC, Herrmann D, Aleshin AE, Ko YH, Cingolani G, Saad JS, Moody DB, Marassi FM, Ehrt S, Niederweis M. 2022. A periplasmic cinched protein is required for siderophore secretion and virulence of Mycobacterium tuberculosis. Nat Commun 13:2255.

Wang Q, Boshoff HIM, Harrison JR, Ray PC, Green SR, Wyatt PG, Barry CE III. 2020. PE/PPE proteins mediate nutrient transport across the outer membrane of Mycobacterium tuberculosis . Science 367:1147–1151.

Lerner TR, Queval CJ, Fearns A, Repnik U, Griffiths G, Gutierrez MG. 2018. Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells. BMC Biol 16:1.

Quigley J, Hughitt VK, Velikovsky CA, Mariuzza RA, El-Sayed NM, Briken V, Kaufmann SHE. 2017. The cell wall lipid PDIM contributes to phagosomal escape and host cell exit of Mycobacterium tuberculosis. mBio 8:e00148-17.

Domenech P, Reed MB. 2009. Rapid and spontaneous loss of phthiocerol dimycocerosate (PDIM) from Mycobacterium tuberculosis grown in vitro: implications for virulence studies. Microbiology (Reading) 155:3532–3543.

Kaps I, Ehrt S, Seeber S, Schnappinger D, Martin C, Riley LW, Niederweis M. 2001. Energy transfer between fluorescent proteins using a co-expression system in Mycobacterium smegmatis. Gene 278:115–124.

Villellas C, Coeck N, Meehan CJ, Lounis N, de Jong B, Rigouts L, Andries K. 2017. Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline. J Antimicrob Chemother 72:684–690.

Saeed DK, Shakoor S, Razzak SA, Hasan Z, Sabzwari SF, Azizullah Z, Kanji A, Nasir A, Shafiq S, Ghanchi NK, Hasan R. 2022. Variants associated with bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naive TB patients in Pakistan. BMC Microbiol 22:62.

Danilchanka O, Mailaender C, Niederweis M. 2008. Identification of a novel multidrug efflux pump of Mycobacterium tuberculosis. Antimicrob Agents Chemother 52:2503–2511.

Nikaido H. 2001. Preventing drug access to targets: cell surface permeability barriers and active efflux in bacteria. Semin Cell Dev Biol 12:215–223.

Domenech P, Reed MB, Barry CE. 2005. Contribution of the Mycobacterium tuberculosis MmpL protein family to virulence and drug resistance. Infect Immun 73:3492–3501.

Viljoen A, Dubois V, Girard-Misguich F, Blaise M, Herrmann JL, Kremer L. 2017. The diverse family of MmpL transporters in mycobacteria: from regulation to antimicrobial developments. Mol Microbiol 104:889–904.

Cortes T, Schubert OT, Rose G, Arnvig KB, Comas I, Aebersold R, Young DB. 2013. Genome-wide mapping of transcriptional start sites defines an extensive leaderless transcriptome in Mycobacterium tuberculosis. Cell Rep 5:1121–1131.

Liu Y, Gao J, Du J, Shu W, Wang L, Wang Y, Xue Z, Li L, Xu S, Pang Y. 2021. Acquisition of clofazimine resistance following bedaquiline treatment for multidrug-resistant tuberculosis. Int J Infect Dis 102:392–396.

Nimmo C, Millard J, van Dorp L, Brien K, Moodley S, Wolf A, Grant AD, Padayatchi N, Pym AS, Balloux F, O’Donnell M. 2020. Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in Southern Africa: a phenotypic and phylogenetic analysis. Lancet Microbe 1:e165–e174.

Fang Z, Sampson SL, Warren RM, Gey van Pittius NC, Newton-Foot M. 2015. Iron acquisition strategies in mycobacteria. Tuberculosis 95:123–130.

Cynamon MH, Klemens SP, Sharpe CA, Chase S. 1999. Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model . Antimicrob Agents Chemother 43:1189–1191.

Escribano I, Rodríguez JC, Llorca B, García-Pachon E, Ruiz M, Royo G. 2007. Importance of the efflux pump systems in the resistance of Mycobacterium tuberculosis to fluoroquinolones and linezolid. Chemotherapy 53:397–401.

Grzegorzewicz AE, Pham H, Gundi VAKB, Scherman MS, North EJ, Hess T, Jones V, Gruppo V, Born SEM, Korduláková J, Chavadi SS, Morisseau C, Lenaerts AJ, Lee RE, McNeil MR, Jackson M. 2012. Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane. Nat Chem Biol 8:334–341.

Belardinelli JM, Yazidi A, Yang L, Fabre L, Li W, Jacques B, Angala SK, Rouiller I, Zgurskaya HI, Sygusch J, Jackson M. 2016. Structure-function profile of MmpL3, the essential mycolic acid transporter from Mycobacterium tuberculosis. ACS Infect Dis 2:702–713.

Jain M, Cox JS. 2005. Interaction between polyketide synthase and transporter suggests coupled synthesis and export of virulence lipid in M. tuberculosis. PLoS Pathog 1:e2.

Converse SE, Mougous JD, Leavell MD, Leary JA, Bertozzi CR, Cox JS. 2003. MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence. Proc Natl Acad Sci U S A 100:6121–6126.

Pacheco SA, Hsu FF, Powers KM, Purdy GE. 2013. MmpL11 protein transports mycolic acid-containing lipids to the mycobacterial cell wall and contributes to biofilm formation in Mycobacterium smegmatis. J Biol Chem 288:24213–24222.

Belardinelli JM, Larrouy-Maumus G, Jones V, Sorio de Carvalho LP, McNeil MR, Jackson M. 2014. Biosynthesis and translocation of unsulfated acyltrehaloses in Mycobacterium tuberculosis. J Biol Chem 289:27952–27965.

Arnold FM, Weber MS, Gonda I, Gallenito MJ, Adenau S, Egloff P, Zimmermann I, Hutter CAJ, Hürlimann LM, Peters EE, Piel J, Meloni G, Medalia O, Seeger MA. 2020. The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature 580:413–417.

Horiyama T, Nishino K. 2014. AcrB, AcrD, and MdtABC multidrug efflux systems are involved in enterobactin export in Escherichia coli. PLoS One 9:e108642.

Vega DE, Young KD. 2014. Accumulation of periplasmic enterobactin impairs the growth and morphology of Escherichia coli tolC mutants. Mol Microbiol 91:508–521.

Bleuel C, Grosse C, Taudte N, Scherer J, Wesenberg D, Krauss GJ, Nies DH, Grass G. 2005. TolC is involved in enterobactin efflux across the outer membrane of Escherichia coli. J Bacteriol 187:6701–6707.

Koch A, Cox H, Mizrahi V. 2018. Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment. Curr Opin Pharmacol 42:7–15.

Ausubel FA, Brent R, Kingston RE, Moore DD, Seidmann JG, Smith JA, Struhl K. 1990. Current protocols in molecular biology. Greene Publishing and Wiley-Interscience, New York.

Smeulders MJ, Keer J, Speight RA, Williams HD. 1999. Adaptation of Mycobacterium smegmatis to stationary phase. J Bacteriol 181:270–283.

Larsen MH, Biermann K, Tandberg S, Hsu T, Jacobs WR. 2007. Genetic manipulation of Mycobacterium tuberculosis. Curr Protoc Microbiol Chapter 10:Unit 10A.2.

Ratledge C, Ewing M. 1996. The occurrence of carboxymycobactin, the siderophore of pathogenic mycobacteria, as a second extracellular siderophore in Mycobacterium smegmatis. Microbiology (Reading) 142 (Pt 8):2207–2212.

Posted 13 Sep 2023 17:31 by | News | No comments

The Center for Global Mental Health Research Webinar Series 2023: Real-World Opportunities and Challenges: Using NIMH’s Research Domain Criteria (RDoC) Framework in Global Mental Health Research

This webinar will discuss the National Institute of Mental Health’s Research Domain Criteria (RDoC) initiative and its potential to inform (and be informed by) global mental health research. RDoC is a research framework that encourages the investigation of mental disorders from a perspective of basic functional dimensions (e.g., cognitive control), using many types of information – from genomics and neuroscience to behavior and environmental measures. The webinar will include an introduction to the RDoC framework and feature presentations from two research groups whose work incorporates RDoC approaches globally.

About the Speakers

Vikram Patel, Ph.D. , is The Pershing Square Professor of Global Health at the Harvard Medical School, where he chairs the Department of Global Health and Social Medicine. He leads the Mental Health for All Lab, which focuses on the social determinant of mental health problems and the use of community resources for their prevention and treatment. He co-founded Sangath, an award-winning Indian NGO that pioneered approaches to achieve mental health equity. He is a Fellow of the UK’s Academy of Medical Sciences and a U.S. National Academy of Medicine member.

Supriya Bhavnani, Ph.D. , is a Co-Principal Investigator in the Child Development Group at Sangath, India. She leads a translational neuroscience research program to develop and validate innovative digital tools, including eye tracking, gamified neuropsychological tasks, and electroencephalography, to assess brain development through the crucial preschool years of early childhood at scale to identify children faltering in their developmental trajectories and enable early interventions. Her research also investigates the determinants of childhood development, focusing on the impact of psychosocial adversities on children’s well-being. She has received the prestigious INSPIRE faculty award and the Innovative Young Biotechnologist Award from the Government of India.

Lerato Majara, Ph.D. , is a postdoctoral research fellow on the Neuropsychiatric Genetics in African Populations (NeuroGAP) project and a member of the Global Initiative of Neuropsychiatric Genetics Education and Research (GINGER) program at Harvard T.H. Chan School of Public Health. Dr. Majara’s research interests are the genetics of psychiatric disorders and the transferability of polygenic risk scores across and within African populations.

Olivia Wootton, M.D.,  is a Ph.D. candidate in the Department of Psychiatry and Mental Health at the University of Cape Town. Her research is focused on the contribution of common genetic variants to cognitive function in the general population and in people with schizophrenia. Dr. Wootton is particularly interested in the clinical relevance of neurogenetic research, including the potential impact of molecular genetics on prognostic and diagnostic assessments and treatment strategies.

Dan J. Stein, M.D., Ph.D. , is a Professor and Chair of the Department of Psychiatry and Mental Health at the University of Cape Town and Director of the South African Medical Research Council’s Unit on Risk & Resilience in Mental Disorders. Dr. Stein is interested in research on anxiety and related disorders, building mental health research capacity in the African context, and working at the intersection of philosophy and psychiatry.

The NIMH RDoC Unit is dedicated to furthering the goals of the RDoC initiative and overseeing various RDoC-related activities. Unit members include Bruce Cuthbert, Ph.D. (Head), Sarah Morris, Ph.D. (Associate Head), Rebecca Berman, Ph.D., Jenni Pacheco, Ph.D., and Syed Rizvi (M.P.H.). Their collective experience spans clinical psychology, public health, cognitive neuroscience, and psychopathology. Together, they collaborate with the RDoC working group and partnering organizations to promote new research approaches to improve mental health.

About the Center for Global Mental Health Research Webinar Series

The Center for Global Mental Health Research, part of the National Institute of Mental Health (NIMH), is hosting a series of webinars focused on applying for and managing global mental health research grants from the National Institutes of Health (NIH). We encourage students, post-docs, and new investigators interested in global mental health research to attend. The webinar series aims to increase knowledge about NIH structure and grant processes and enhance global mental health research capacity.

Sponsored by

The Center for Global Mental Health Research

For questions about meeting logistics, difficulties registering, or problems accessing the webinar, please email [email protected].

For questions about the webinar content, please send emails to [email protected].

Posted 13 Sep 2023 15:31 by | News | No comments

Mit MagentaTV Zugriff auf alle Streaming-Dienste

Nur bei MagentaTV (https://www.telekom.de/zuhause/fernsehen) finde ich die Inhalte aller Streaming-Dienste* auf einer Oberfläche ohne in separaten Apps suchen zu müssen. Die übergreifende Such- und Browsingfunktion erleichtert das Suchen, Finden und Konsumieren.

*Streaming-Dienste erfordern einen separaten Vertrag

Tagged:

Posted 13 Sep 2023 13:39 by | News | No comments

Busing Issues Addressed at First Montclair BOE meeting – Montclair Local

Austin Pacheco via Unsplash

At the first Board of Education meeting of the 2023-2024 school year, the Board wasted no time addressing the transportation issues many parents and students faced on the first day of school. Many students started the year without a bus assignment or route listed in Genesis.

BOE President Allison Silverstein said, “It was unfortunate that this was an issue even before I was on the Board of Education, I would stand there at that podium, discuss transportation of our students, especially our special education students, and year after year, there are issues.”

Silverstein said her child was one of the students who went without a bus assignment. Superintendent, Dr. Jonathan Ponds, addressed the issue and stated that the district takes full accountability and will not make any excuses for the mishap.

Supervisor of Transportation Sheila Maurice apologized and explained that over the summer the district upgraded their transportation system from Routefinder Pro to Routefinder Plus, and said some of the transportation information did not transfer over from the student’s database to the parent’s. Maurice said parents can expect the issue to be resolved by noon Friday. Next year, Maurice said parents will receive student transportation assignments before September 1. 

The Board also approved the first reading of The School Threat Assessment Teams. With this policy, every school in the district will assist faculty and staff to identify students of concern and assess students at risk for engaging in violence or other harmful activities. The threat assessment team is expected to include: a school employee with expertise in student counseling such as a school counselor, school social worker, or school counselor; a teaching staff member; a Principal or other senior school administrator; a school resource offer or school employee who serves as liaison to law enforcement; and the school safety specialist. 

The next Board of Education meeting will take place on Monday, September 18.

At the first Board of Education meeting of the 2023-2024 school year, the Board wasted no time addressing the transportation issues many parents and students faced on the first day of school. Many students started the year without a bus assignment or route listed in Genesis.

BOE President Allison Silverstein said, “It was unfortunate that this was an issue even before I was on the Board of Education, I would stand there at that podium, discuss transportation of our students, especially our special education students, and year after year, there are issues.”

Silverstein said her child was one of the students who went without a bus assignment. Superintendent, Dr. Jonathan Ponds, addressed the issue and stated that the district takes full accountability and will not make any excuses for the mishap.

Supervisor of Transportation Sheila Maurice apologized and explained that over the summer the district upgraded their transportation system from Routefinder Pro to Routefinder Plus, and said some of the transportation information did not transfer over from the student’s database to the parent’s. Maurice said parents can expect the issue to be resolved by noon Friday. Next year, Maurice said parents will receive student transportation assignments before September 1. 

The Board also approved the first reading of The School Threat Assessment Teams. With this policy, every school in the district will assist faculty and staff to identify students of concern and assess students at risk for engaging in violence or other harmful activities. The threat assessment team is expected to include: a school employee with expertise in student counseling such as a school counselor, school social worker, or school counselor; a teaching staff member; a Principal or other senior school administrator; a school resource offer or school employee who serves as liaison to law enforcement; and the school safety specialist. 

The next Board of Education meeting will take place on Monday, September 18.

Posted 13 Sep 2023 12:31 by | News | No comments

A Closed Door, Slightly Ajar – This Week’s Links

We’re in for a busy weekend of comics events, and, coming from a relatively tiny country, that you can drive across in a matter of hours, I have to assume that you could fairly easily have planned a trip that would allow you to travel between the Small Press Expo and Baltimore Comic-Con, having spent the last couple of days at the National Cartoonist Society’s Reuben events in New Jersey, on a single tank of petrol and still be home in time for tea after taking in the sights – if that isn’t the case, well, then there’s this week’s links, below, instead.

The Veldt pic.twitter.com/cCxY3m5eYF

— 🎃🍂🦤Holly🦤🍂🎃 (@SparrowLucero) September 4, 2023

This week’s news.

• Collective bargaining news, and United Workers of Seven Seas, the union of employees of publisher Seven Seas Entertainment, announced at the end of last month that they have voted to ratify their first contract, following the voluntary recognition of the union last summer – UW7S’ goals, as stated during their formation, can be read here.

• Comics prize news, ahead of this weekend’s parallel announcements of the winners of the 2023 Ignatz Awards and the Ringo Awards, and Broken Frontier shared London’s Cartoon Museum’s announcement of the winners of this year’s Alison Brown Young Comics Maestro Award, with nods given to Sofia Deen, Eric Caseras-Ros, Zack Bennett, Asta Haldane, recognising them as some of “the most exciting comic strip talents from the UK under the age of 18 years old.”

• Elsewhere, The Daily Cartoonist shares the winners of the National Cartoonist Society’s annual Reuben Awards, with Bill Griffith named as 2022’s Cartoonist of the Year – The Daily Cartoonist provide a full round-up of divisional award winners here.

• Koyama Provides announced their next wave of grants, meant this time round as “encouragement to persevere” to artists, rather than being linked to specific projects, with $1500 awards given to T Edward Bak, Rosena Fung, Benjamin Marra, and Alicia Nauta.

We’re getting excited for this week’s Reuben Awards. The big “Cartoonist of the Year” will be handed out by none other than Garfield creator, JIM DAVIS!https://t.co/vKPuSUgmDW pic.twitter.com/26UmLkLCYQ

— National Cartoonists Society (@NatCartoonSoc) September 5, 2023

This week’s reviews.

TCJ

Nicholas Burman reviews the major themes of Alec Robbins’ Mr. Boop – “Humor is only part of the picture, however, as a lot of the time there’s actually quite a wholesome quality to everything. It’s lewd and strange, but the general sentiment is that this couple is genuinely head over heels for each other – they talk things out, and they work on their problems together. It’s all quite sex-positive, which is maybe the biggest twist on the Betty Boop character that one could do.”

AIPT

• Piper Whitaker reviews the strong setting for Joanne Starer, Natacha Bustos, et al’s Fire & Ice: Welcome To Smallville #1.

• Lia Williamson reviews the promising elements of Kelly Thompson, Leonardo Romero, et al’s Birds of Prey #1.

• Lukas Shayo reviews the effective return of  Josh Trujillo, Adrián Gutiérrez, et al’s Blue Beetle #1.

• David Brooke reviews the new directions of Kieron Gillen, Paco Medina, et al’s Immortal X-Men #15.

• Keigen Rea reviews the refreshing changes of Al Ewing, Ram V, Cafu, et al’s Venom Volume 4: Illumination.

• Colin Moon reviews the flat finale of Kelly Thompson, Sergio Dávila, et al’s Captain Marvel: Revenge of the Brood Part 2.

• Collier Jennings reviews the compelling darkness of Ethan S. Parker, Griffin Sheridan, Bob Quinn, et al’s Kill Your Darlings #1.

• Ronnie Gorham reviews the exhilarating entertainment of Jay Baruchel, Van Jansen, Alessandro Micelli, et al’s Tear Us Apart #1.

The Beat

• Liz Davis reviews the grounded reality of Anthony Del Col, Fahmida Azim, et al’s I Escaped a Chinese Internment Camp.

• Tim Rooney reviews the ambitious beginning of Ethan S. Parker, Griffin Sheridan, Bob Quinn, et al’s Kill Your Darlings #1.

• Cy Beltran reviews the disorienting leaps of Karla Pacheco, Rosi Kämpe, Marika Cresta, et al’s Spider-Gwen Annual #1.

• Marion Pena reviews the enjoyable banter of Johnny O’Bryant, Vaughn Alexander, Corey Mikeil, Nic Macari, Sebas Riera, et al’s Primus7: Volume 1.

Broken Frontier

Andy Oliver has reviews of: 

– The freeform eloquence of Joe Kessler’s The Gull Yettin. 

– The genre blending of Olivia Stephens’ Darlin’ and Her Other Names Part 1: Marta.

– The distinctive voice of Caroline Cash’s PeePee-PooPoo #420.

– The atmospheric cartooning of Paul B. Rainey’s Why Don’t You Love Me?.

Four Color Apocalypse

Ryan Carey reviews the endearing weirdness of David G. Caldwell’s Yankee Doodle Strangler 2 vs Tanka Truk.

House to Astonish

Paul O’Brien has capsule reviews of Marvel Comics’ X-Men Unlimited Infinity Comic #102, Wolverine #36, MS. Marvel: The New Mutant #1, Deadpool: Badder Blood #3, and Love Unlimited Infinity Comic #65.

Multiversity Comics

• Christopher Egan reviews the clunky construction of Zac Thompson, Valeria Burzo, et al’s Hunt for the Skinwalker #1.

• Robbie Pleasant reviews the impressive celebration of BOOM! Studios’ Mighty Morphin’ Power Rangers 30th Anniversary Special.

Notable Graphic Novels Review

• Door Williams reviews the delightful setting of Talia Dutton’s M is for Monster.

• Steph Noell reviews the masterful choices of Melanie Gillman’s Other Ever Afters: New Queer Fairy Tales.

• Erin Carney reviews the tender compassion of Lewis Hancox’s Welcome to St. Hell: My Trans Teen Misadventure.

• June Bendich reviews the diverse messaging of IDW’s Voices That Count: A Comics Anthology by Women.

• Shandy Frey reviews the rewarding realness of Jamila Rowser and Robyn Smith’s Wash Day Diaries.

Publisher’s Weekly

Have capsule reviews of:

– The bracing rendering of Edel Rodriguez’s Worm: A Cuban American Odyssey.

– The breakneck pace of Tom Scioli’s I Am Stan: A Graphic Biography of the Legendary Stan Lee.

– The essential extremes of Yoshiharu Tsuge’s Nejishiki, translated by Ryan Holmberg.

– The vital resonance of Fujiwara Maki’s My Picture Diary, translated by Ryan Holmberg.

– The profound portrait of Emily Bowen Cohen’s Two Tribes.

– The nuanced drama of Samuel Sattin and Rye Hickman’s Buzzing.

Solrad

Hagai Palevsky reviews the stylistic subversions of Daria Tessler’s Salome’s Last Dance.

Just coloured this Conan piece that @davidrubin posted a couple of weeks ago. pic.twitter.com/XGI2258NWN

— Mark Dale IT’S ONLY TEENAGE WASTELAND TPB OUT NOW (@pleurgh) September 6, 2023

This week’s interviews.

TCJ

John Kelly interviews Bill Griffith about Three Rocks: The Story of Ernie Bushmiller – The Man Who Created Nancy and The Buildings are Barking: Diane Noomin in Memoriam – “There’s thousands, or hundreds, of dumb comic strips. Nancy isn’t one of them. It’s in no way one of them. It’s actually– it’s not sophisticated in the sense that literature is sophisticated, but it is highly sophisticated. In the comic language that it speaks, it really speaks a language, and that language is what you respond to, whether you’re aware of it or not.”

AIPT

• Chris Hassan speaks with Louise Simonson about Jean Grey, the origins of the series, and returning to iterate on a character with so much continuity.

• Chris Coplan talks to Anya Davidson about Night and Dana, the big questions of genre fiction, the horror of climate change, and the lives of crones.

The Beat

• Avery Kaplan interviews refrainbow about Boyfriends, spicing up established archetypes, editing out copyrighted references for print, and favourite Pokémon.

• Taimur Dar speaks with Jeremy Adams about Jay Garrick: The Flash, similarities between writing for comics and animation, and bringing characters back from the dead.

Forbes

Rob Salkowitz chats with Scott Hoffman about Wag, genre fiction origins, collaborative endeavours, and being mentored by Phil Jimenez.

Publisher’s Weekly

DW McKinney talks to Ibram X. Kendi and Joel Christian Gill about Stamped from the Beginning, and how the graphic adaptation of the book came together.

Smash Pages

JK Parkin interviews Mat Groom about Inferno Girl Red, building out the Massive-verse, returning to crowdfunding, and keeping your backers updated.

The Vinyl Factory

Kelly Doherty speaks with Thomas Maucéri and Sébastian Piquet about In Search of Gil Scott-Heron, the origins of the book, and the project’s peculiar connections.

Women Write About Comics

Adrienne Resha talks to Sabir Pirzada about Ms. Marvel: The New Mutant, the collaborative process for the book, and where Kamala Khan is going from here.

A little comic detailing @heyriette first time volunteering at MICE (1/2) pic.twitter.com/5cJXQAdo4u

— Massachusetts Independent Comics Expo (@MassMICE) August 31, 2023

This week’s features and longreads.

• Here at TCJ, Austin Price writes on personal history with Masami Kurumada’s Saint Seiya, time spent captured in the series’ orbit, and returning to it at a remove now it is readily available once more – “To dismiss as impossible the idea that a work—let alone a genre—might be both cynical and earnest at the same time is to misunderstand what earnestness means and what it is used to represent. Because earnestness is not a measure of the “honesty” of a work or a metric for determining some quotient of truth. Similarly so sincerity. They are poses, suggestions, affects that rely on an aggressive enthusiasm to stand in as an empty signifier for a “truth” they can prove in no other way.”

• For The Beat, Heidi MacDonald continues a look at the state of the direct market in 2023, with comments from Comichron’s John Jackson Miller, and the current difficulties in accurately assessing sales figures.

• Elizabeth Sandifer’s Last War in Albion returns, as Alan Moore’s plans for work post-Watchmen result in a dive into the history of the shopping mall, with The Mandelbrot Set/Big Numbers looming.

• For Australia’s ABC, Matt Neal writes on 60 years of the X-Men, and the themes of diversity and inclusion that have come to embody the various series featuring Marvel’s mutants over the decades.

• Shelfdust’s retrospective on Si Spurrier and Matias Bergara’s John Constantine: Hellblazer continues, as this week Mo Ali looks back at issue ten of the series, and the fractured aspects of its engagement with the magic of identity.

• For Women Write About Comics, Dayn Broder has an essay on the history of DC comics’ Barbara Gordon, the evolution of the character, accurate depictions of wheelchair use, and portrayals of disability in superhero comics thus far.

• Over at Broken Frontier, Simon Russell starts a new series of behind-the-scenes features, looking at comics works in progress, this week profiling Myfanwy Tristram and the making of The Noisy Valley.

• Another new series, starting at House to Astonish, as Paul O’Brien surveys the back catalogue of one Matthew Murdoch, in an attempt to more fully catalogue the various villains of Daredevil.

• From the world of open-access academia, Ellen Kirkpatrick’s book Recovering the Radical Promise of Superheroes: Un/Making Worlds is available to read for free, speculating on the (sometimes thwarted) questions posed by superhero narratives.

• In the Journal of Graphic Novels and Comics, Dan Santos and Anna-Sophie Jürgens write on Stjepan Šejić’s Harleen, and the manner in which DC comics have utilised Quinzel’s background as a scientist in the character’s eventual transformation into Harley Quinn.

• Mike Peterson rounds up the week’s editorial beat, over at The Daily Cartoonist, as upcoming elections, Labor Day breaks, the passing of Jimmy Buffet, and ageing politicians all fell under the spotlight.

Get your tickets to SPX 2023 happening this weekend: https://t.co/CMdWTiuWJd

— SMALL PRESS EXPO (@SPXcomics) September 6, 2023

This week’s audio/visual delights.

• The New York Comics & Picture-Story Symposium returned with an autumnal slate of programming, kicking things off with a conversation between Ben Katchor and Gary Groth, moderated by Austin English, as they spoke about their personal paths through comics, as both consumers and professionals.

• For those unable to attend this weekend’s Small Press Expo, you can recreate a little bit of the experience at home, if your usual event experience would be watching videos on an electronic device, with last year’s talks and panels.

• David Brothers hosted the latest edition of Mangasplaining, as this week’s read was Takehiko Inoue’s Real Volume 13, with discussion of Inoue’s other basketball series, Slam Dunk and Buzzer Beater, and volume 13’s focus on wrestling.

• Gil Roth welcomed Peter Rostovsky to this week’s edition of The Virtual Memories Show, as they spoke about Damnation Diaries, the origins of the book, history with the comics medium, and art studio communities.

• David Harper was joined by Jed McKay for the latest episode of Off Panel, as they discussed problem solving and current projects for the House of Ideas, editorial impact, penning a new first issue and taking over after a long run, and collaborative endeavours.

• A couple of visits to John Siuntres and the Word Balloon, as Gamal Hennessy joined proceedings to talk about The Business of Freelance Comic Book Publishing and the realities behind getting work, and with Mark Pracht and Sean Harklerode about the new play The Innocence of Seduction and its depiction of the 1950s Congressional investigation into the comic book industry.

• Closing out the week with some more Cartoonist Kayfabe, as Jim Rugg and Ed Piskor took a look at Kentaro Miura’s Berserk: Deluxe Edition Volume 1, Todd McFarlane and Greg Capullo’s Spawn #29, 1996’s Wizard #58, Katsuhiro Otomo’s The Complete Works, and Helen McCarthy’s The Art of Osamu Tezuka.

dog pic.twitter.com/WiPEfbnXtY

— Yuming Li (@_Yuming_Li) August 30, 2023

That’s all for this week, because it’s too hot, and my laptop sounds like it’s about to take off.

Want to win a copy of Monica and an exclusive print signed by @danielclowes? Head to our Instagram to enter to win! https://t.co/gRygVorGdJ pic.twitter.com/sLYJczLF6A

— Fantagraphics (@fantagraphics) September 5, 2023

The post A Closed Door, Slightly Ajar – This Week’s Links appeared first on The Comics Journal.

Posted 13 Sep 2023 11:31 by | News | No comments

Internet Designing Essentials

Internet Designing Essentials

To understand website design significance, allow us initially contrast an inadequately made web page from that of an exceptional one.

Badly made web page is easy, direct, complex, pitiful as well as does not have focus on information. Therefore, it will certainly refrain you any kind of excellent. It will certainly simply be a wild-goose chase as well as initiative.

On the various other hand, a superior web page is energetic, nonlinear, constant and also tidy with its design and also information. This kind of web page can drag your ecommerce to complete blast.

Currently, allow us talk about the importance of each necessary top quality.

Interactivity

This top quality enables the visitor to take part proactively as well as voluntarily. Instances of interactive tool are the following: examinations, hypermedia, hypertext, video games, chatroom as well as the sort.

To be energetic with the website urges review. This is since site visitors are eager sufficient to recognize whether this website is pleasurable or otherwise, academic or crap as well as welcoming or drooping.

Linear Organization

Hence, do not make your internet page extra uninteresting than a publication as well as tough to check out like a technological thesis. Class ambience time-outs site visitor to rest, be certain to organize your web page in a method that it will certainly not be to tiring on them to review your web page.

Focus on Details

There need to be uniformity regarding information. On the academic element, cognitive loading, sequencing of info, responses as well as incorrect message have to be prevented considering that they stand for negative style.

On the technological element, damaged web links, inadequate navigating as well as non-active tips are frustrating. Therefore, if you wish to integrate the exact same right into your layout, make sure they are operating well so as not to irritate the site visitors.

Graphic User Interface

High quality is your upper top priority. Visuals customer interface have to not be neglected. To provide you a tip, do not make use of plain shades, prevent hectic displays as well as the overuse of graphics as well as computer animations.

Ecommerce internet advancement is important to your websites. Make certain to use them properly and also truly.

Badly made web page is easy, straight, complicated, useless as well as does not have focus on information. Therefore, do not make your internet page a lot more dull than a publication as well as hard to check out like a technological thesis. Class environment time-outs site visitor to rest, be certain to prepare your web page in a method that it will certainly not be to exhausting on them to review your web page.

Visuals customer interface have to not be ignored. To provide you a tip, do not make use of boring shades, stay clear of hectic displays as well as the overuse of graphics and also computer animations.

Posted 13 Sep 2023 11:03 by | Uncategorized | No comments

Months after release at Martinez refinery, county prepares final health assessment

Contra Costa Health is asking for the public to offer comments on the findings from a third-party analysis of the allegedly hazardous materials released from the Martinez Refining Company last November.

The refinery released spent catalyst on Nov. 24 and 25, 2022.

There will be a public hearing on the report — which has not yet been officially accepted by the Contra Costa County Board of Supervisors — from 6 to 8 p.m. Sept. 25 at the county administration building.

CCH announced in June an independent toxicologist found the release did not increase public health risks from exposure to nearby soil.

But the analysis didn’t take into account any health effects to the public during the release, which lasted from Thanksgiving night until the next day and released an estimated 20 to 24 tons of material into the community.

The refinery didn’t alert the county or the community warning system as required by law, and residents found cars and homes covered in dust, samples of which showed elevated levels of aluminum, barium, chromium, nickel, vanadium, and zinc, all of which can cause respiratory problems. CCH found out about the release via social media reports a day-and-a-half after it started.

Investigation ongoing

The Contra Costa County District Attorney’s Office is still investigating MRC for failing to notify authorities about the release.

County supervisors put together an oversight committee, including residents from affected areas, to investigate whether the release increased risk of health problems in the community due to environmental contamination. The panel is also looking at what caused the release.

Health officials stress the report is not an investigation into the spent catalyst release. The report includes results of soil sampling and evaluation of the levels of metals found in the samples compared to published sources of soil health standards and regional background levels for naturally occurring metals found in the catalyst dust.

At the Sept. 25 meeting, Contra Costa County’s Hazardous Material Programs will discuss the findings from the evaluation and receive public comment about the report, CCH said in a statement.

The public comment period remains open until Oct. 12.

Comments on the report can be sent to [email protected]. Comments can be mailed to Michael Dossey at Contra Costa Health Hazardous Materials Programs, 4585 Pacheco Blvd., Suite 100, Martinez, CA 94553.

The post Months after release at Martinez refinery, county prepares final health assessment appeared first on Local News Matters.

Posted 13 Sep 2023 10:31 by | News | No comments

DTI exec placed on ‘floating status’

A case filed with the Ombudsman has prompted the transfer of Trade Undersecretary Ruth Castelo from the Consumer Protection Group to the Office of the Secretary, resulting in her being on “floating status,” a source at the Department of Trade and Industry, or DTI, said Saturday.

“Castelo was reassigned to the OSEC. In the meantime, the informant told Daily Tribune, “ Assistant Secretary Jean Pacheco was designated OIC (officer in charge) of the CPG so as not to impede its operations,” the informant told Daily Tribune.

Castelo’s reassignment stemmed from a case that was filed against her and other high-ranking officials of the DTI, the source said, “as Secretary Alfredo Pascual does not want to be accused of not playing fair by any party.”

“If Usec. Ruth stays with the CPG, there might be allegations of unduly influencing or manipulating certain documents included in the complaint. The secretary wanted to be impartial and fair,” according to the source.

She said Castelo remains an undersecretary but does not have any portfolio.

Steelmaker filed case

Last month, Castelo, along with DTI-Bureau of Philippine Standards Director Neil Catajay, DTI-BPS officer-in-charge Ferdinand Manfoste, DTI-BPS Enforcement Team chief Engineer John Steven Magboo, staffers Sarah Jane Arella, Alyssa Marie Frayre and Phillip Sawali, and five members of the DTI-FTEB Enforcement Team were sued before the Office of the Ombudsman-Mindanao by Davao TYT Lucky Steel Corp., represented by its president and manager Jennifer “Wingki” Qua.

They were accused of violating Section 3(e) of Republic Act 3019, or the Anti-Graft and Corrupt Practices Act, as well as of grave misconduct, serious dishonesty, grave abuse of authority, and conduct prejudicial to the best interest of the service.

The complaint stemmed from Sawali’s alleged order, approved by Castelo on 9 June, authorizing a raid on Davao TYT Lucky Steel Corp. last 22 June.

The DTI team stormed the company’s warehouse in Barangay San Isidro, Bunawan District, Davao City, and seized 176,497 pieces of Lucky Fence Tube that the company had imported.

The raid was questioned by Qua in a letter to Secretary Pascual on 23 June that stated that there was no deception in connection with the presence of threads on the ends of Lucky Fence Tubes.

“Presently, there is no applicable standard for fence tubes. PNS 2145:2000 is not yet in effect, and its implementation is scheduled for July 2024. Therefore, until this standard comes into force, there can be no violation of selling tubes with threads. Due to these reasons, the monitoring and enforcement actions undertaken by Castelo and her raiding team were downright illegal,” Qua said in her letter to Pascual.

The post DTI exec placed on ‘floating status’ appeared first on Daily Tribune.

Posted 13 Sep 2023 05:31 by | News | No comments

Buy Colloidal Silver (2 )

Acquire Colloidal Silver

Colloidal silver is little sufficient to be able to bypass the gastrointestinal procedure and also get in the blood stream. It is created via an electro-magnetic procedure which draws little bits of silver from a bigger example of pure silver right into a fluid base (normally distilled water).

After electrolysis, these silver bits continue to be in suspension since the electrical fee in each atom is more powerful than the activities of gravity, stopping them from clearing up at the end of the container. This after that enables the bits to relocate easily around in the body.

One of the most crucial advantage of colloidal silver is its antimicrobial residential properties. For many years, silver colloids have actually been made use of for a variety of therapies, consisting of therapy for illness such as skin infections and also colds.

In 1938, the usage of colloidal silver was reduced by the Food and also Drug Administration (FDA) obviously since of its reported poisoning although several think that it was since the option was endangering the anti-biotics sector.

Consequently, colloidal silver obtained the standing of a pre-1938 medication, which indicates that you can acquire colloidal silver in the marketplace however just as it was made use of and also as it was made. To put it simply, manufacturers of colloidal silver can not make any type of restorative or medical insurance claims regarding their items without having the FDA knocking at their door.

Amongst these are silver nitrate as well as a plaster that guides silver ions right into the afflicted location to speed up recovery and also stop infections. Up until after that, you can acquire colloidal silver just as a nutritional supplement.

Below are a couple of internet sites where you can get colloidal silver:

Shopping.com

You can get colloidal silver items at costs varying from $13 to 26:

* Futurebiotics Silver 4 oz.
* Ultra-Colloidal Gold 50 ppm 16 oz.
* Sovereign Silver, Colloidal Silver Hydrosol (Fine Mist Spray) 10 ppm, 2 oz.
* Vibrant Health Colloidal Silver
* Source Naturals Colloidal silver 10 ppm 2 fl. Oz.
* Colloidal Silver Wellness Throat Spray 30 ppm 2 fl. Oz.

Amazon.com

An additional excellent website to purchase colloidal silver is Amazon.com. Offered items consist of:

* Natural Path Silver Wings Dietary Mineral Supplement, Colloidal Silver, 500 ppm 4 oz.
* Colloidal Silver Nasa Spray 2 oz. (Sovereign Silver).
* Source Naturals Wellness Colloidal Silver, 30 ppm 8 fl oz.
* Trimedica Colloidal Silver 16 fl oz.
* Trace Minerals Research Liquimins Colloidal Silver 8 fl oz.

There are lots of even more areas where you can purchase colloidal silver. An option would certainly be to go straight to the internet sites of colloidal silver makers and also order from them.

Amongst these are silver nitrate as well as a plaster that guides silver ions right into the damaged location to speed up recovery and also stop infections. With this existing pattern, it looks like colloidal silver might quickly acquire ground in traditional medication. Up until after that, you can purchase colloidal silver just as a nutritional supplement.

There are several even more areas where you can get colloidal silver. An option would certainly be to go straight to the sites of colloidal silver suppliers as well as order from them.

Posted 13 Sep 2023 04:03 by | Uncategorized | No comments

« Previous Page — Next Page »